| 货号 | 1127/1G |
| 别名 | 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | α2-adrenoceptor antagonist (pKi values are 8.52, 8.00 and 9.17 for human α2A,α2Bandα2C receptors respectively). Diastereomer Rauwolscine hydrochloride (Cat. No. 0891) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 390.91 |
| 分子式 | C21H26N2O3 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| 参考文献 | Lalchandaniet al (2002) Yohimbine dimers exhibiting selectivity for the human α2c-adrenoceptor subtype. J.Pharmacol.Exp.Ther. 303 979. PMID: 12438517. Redfern and Williams (1995) A re-evaluation of the role of α2-adrenoceptors in the anxiogenic effects of yohimbine, using the selective antagonist delequamine in the rat. Br.J.Pharmacol. 116 2081. PMID: 8640349. Goldberg and Robertson (1987) Yohimbine: a pharmacological probe for study of the α2-adrenoceptor. Pharmacol.Rev. 35143. Doxeyet al (1984) Comparison of the α-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine. Naunyn Schmiedebergs Arch.Pharmacol. 325 136. PMID: 6144048. |