货号 | 2918/50 |
别名 | 4α,9-Epoxy-3β-veratroyloxy-5β-cevan-4β, |
是否允许进口 | 否 |
是否危险品 | 是 |
供应商 | Tocris |
生物活性 | Voltage-gated Na+ channel opener; increases intracellular Ca2+ with no effect on the Na+/Ca2+ exchanger. Steroid-derived alkaloid neurotoxin. Increases membrane Na+ permeability and depolarizes excitable tissues. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 673.79 |
分子式 | C36H51NO11 |
可溶性/溶解性 | Soluble to 50 mM in DMSO |
参考文献 | Feketeet al (2009) Mechanism of the persistant sodium current activator veratridine-evoked Ca2+ elevation: implication for epilepsy. J.Neurochem. 111 745. PMID: 19719824. Marotoet al (1994) Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine. Eur.J.Pharmacol. 270 331. PMID: 7805782. McKinneyet al (1986) Purification, solubility and pKa of veratridine. Anal.Biochem. 153 33. PMID: 3963380. |