| 货号 | 2459/50 |
| 别名 | (3-endo)-8-Methyl-8-azabicyclo[3.2. |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Potent, orally active 5-HT3 receptor antagonist. Antiemetic. Also partial agonist of α7 nAChR. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 320.82 |
| 分子式 | C17H20N2O2 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 50 mM in DMSO |
| 参考文献 | Mhatreet al (2004) 5-HT3 antagonist ICS 205-930 enhances naltrexone's effects on ethanol intake. Eur.J.Pharmacol. 491 149. PMID: 15140631. Papkeet al (2004) Activity of α7-selective agonists at nicotinic and serotonin 5HT3receptors expressed in Xenopusoocytes. Bioorg.Med.Chem.Lett. 14 1849. PMID: 15050614. Middlemiss and Tricklebank (1992) Centrally active 5-HT receptor agonists and antagonists. Neurosci.Biobehav.Rev. 16 75. PMID: 1553108. Seynaeveet al (1991) 5-HT3 receptor antagonists, a new approach in emesis: a review of ondansetron, granisetron and tropisetron. Anticancer Drugs 2 343. PMID: 1665723. |