| 货号 | 4108/50 |
| 别名 | (S)-(6-Methoxyquinolin-4-yl)((2R,4S |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Class IA antiarrythmic; reduces both Na+ and K+ channel currents, including INa, IKr and IKs. Prolongs QT and induces torsade de pointes (TdP). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 324.42 |
| 分子式 | C20H24N2O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| 参考文献 | Wuet al (2008) Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine. Heart Rhythm. 5 1726. PMID: 19084812. Borggrefeet al (2005) Short QT syndrome genotype-genotype correlations. J.Electrocardiol. 38 75. PMID: 16226079. Caballeroet al (2003) Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines. Br.J.Pharmacol. 138 1475. PMID: 12721103. |