| 货号 | 1125/100 |
| 别名 | 2-(3,4-Dihydroxyphenyl)-3,5,7-trihy |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Antitumor agent; induces apoptosis and inhibits synthesis of heat shock proteins. Inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Can also activate Ca2+ and K+ channels and behaves as an agonist at estrogen (GPER) receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 302.24 |
| 分子式 | C15H10O7 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Cermaket al (2002) The flavonol quercetin activates basolateral K+ channels in rat distal colon epithelium. Br.J.Pharmacol. 135 1183. PMID: 11877325. Saponaraet al (2002) Quercetin as a novel activator of L-type Ca2+ channels in rat tail artery smooth muscle cells. Br.J.Pharmacol. 135 1819. PMID: 11934824. Weiet al (1994) Induction of apoptosis by quercetin: involvement of heat shock protein. Cancer Res. 54 4952. PMID: 8069862. Levyet al (1984) Tyrosine protein kinase activity in the DMBA-induced rat mammary tumor: inhibition by quercetin. Biochem.Biophys.Res.Commun. 123 1227. PMID: 6091650. Grazianiet al (1983) The effect of quercetin on the phosphorylation activity of the Rous sarcoma virus transforming gene product in vitroandin vivo. J.Biochem. 135 583. PMID: 6311542. Merck Index 128216. |