| 货号 | 1446/25 |
| 别名 | N-(bis-3-chloro-4-hydroxybenzyl)-5Z |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of anandamide uptake (IC50 = 17.3 μM) with little or no activity at CB1, CB2, TRPV1 and FAAH. Intravenous administration inhibits limb spasticity in mice with chronic relapsing experimental allergic encephalomyelitis (CREAE). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 584.62 |
| 分子式 | C34H43Cl2NO3 |
| 可溶性/溶解性 | Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml) |
| 参考文献 | Ligrestiet al (2006) New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis. Br.J.Pharmacol. 147 83. PMID: 16284631. Di Marzoet al (2002) A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. J.Pharmacol.Exp.Ther. 300 984. PMID: 11861807. Griffinet al (2001) Activity of a novel anandamide analog suggests a non-CB1, non-VR1 site of action. 2001 Symposium on the Cannabinoids, International . |