货号 | 4312/10 |
别名 | (2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,7R |
是否允许进口 | 否 |
是否危险品 | 是 |
供应商 | Tocris |
生物活性 | Potassium ionophore, exchanges K+ for H+ across biological membranes, in a similar manner to Valinomycin (Cat. No. 3373). Stimulates mitochondral ATPase activity and disrupts membrane potential. Also acts as an ionophore for Pb2+ with no activity with other divalent cations. Antibiotic derived from Streptomyces hygroscopius. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 746.94 |
分子式 | C40H67NaO11 |
可溶性/溶解性 | Soluble to 100 mM in ethanol |
参考文献 | Hamidiniaet al (2004) The ionophore Nigericin transports Pb2+ with high activity and selectivity: A comparison to Monensin and Ionomycin. Biochemistry. 43 15956. PMID: 15595852. Eytanet al (1990) Energy-linked transhydrogenase: Effects of Valinomycin and Nigericin on the ATP-driven transhydrogenase reaction catalyzed by reconstituted transhydrogenase-ATPase vesicles. J.Biol.Chem. 2212949. |