| 货号 | 4112/50 |
| 别名 | 2-[3-(Trifluoromethyl)anilino]nicot |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Nonsteroidal anti-inflammatory drug (NSAID); selectively inhibits COX-2. Also activates human TRPA1 inducibly expressed in HEK293 cells; displays agonist activity at GPR35. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 282.22 |
| 分子式 | C13H9F3N2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Denget al (2012) Multiple tyrosine metabolites are GPR35 agonists. Sci.Rep. 2 373. PMID: 22523636. Huet al (2010) Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs. Pflugers Arch. 459 579. PMID: 19888597. Famaey (1997) In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. Inflamm.Res. 46 437. PMID: 9427063. Ottolia and Toro (1994) Potentiation of large conductance KCa channels by niflumic, flufenamic and mefenamic acids. Biophys.J. 67 2272. PMID: 7535111. |