货号 | 3258/10 |
别名 | [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(ami |
是否允许进口 | 否 |
是否危险品 | 是 |
供应商 | Tocris |
生物活性 | Antibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis. Also used for MEF/STO feeder layer preparation in stem cell culture. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 334.33 |
分子式 | C15H18N4O5 |
可溶性/溶解性 | Soluble to 5 mM in water and to 100 mM in DMSO |
参考文献 | Parket al (2016) Modeling and correction of structural variations in patient-derived iPSCs using CRISPR/Cas9. Nat.Protoc. 11 2154. PMID: 27711053. Bryjaet al (2006) Derivation of mouse embryonic stem cells. Nat.Protoc. 1 2082. PMID: 17487198. Bizaneket al (1992) Isolation and structure of an intrastrand cross-link adduct of mitomycin C and DNA. Biochemistry 31 3084. PMID: 1554696. Tomaszet al (1987) Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science 235 1204. PMID: 3103215. |