| 货号 | 4052/50 |
| 别名 | N'-[(8α)-9,10-Didehydro-6-methylergol |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Dopamine receptor agonist and anti-Parkinson's agent. Displays high affinity for D2, D3 and D4 receptors along with 5-HT1A. Exhibits some 5-HT2B receptor antagonist properties. Decreases prolactin release; reduces inflammatory mediators such as TNF-α and IL6. Exhibits anticonvulsive effects. Acts similar to bromocriptine (Cat. No. 0427). |
| 运输条件 | Ambient |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 454.52 |
| 分子式 | C20H26N4O.C4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Zweckbergeret al (2010) Anticonvulsive effects of the dopamine agonist lisuride maleate after experimental traumatic brain injury. Neurosci.Lett. 470 150. PMID: 20056133. Hofmannet al (2006) Lisuride, a dopamine receptor agonist with 5-HT2B receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-HT2B receptor agonism in cardiac valvular fibrosis. Clin.Neuropharmacol. 29 80. PMID: 16614540. Woitallaet al (2004) Transdermal lisuride delivery in the treatment of Parkinson's disease. J.Neural Transm. 6889. |