货号 | 1103/100 |
别名 | cis-1-Acetyl-4-[4-[[2-(2,4-dichloro |
是否允许进口 | 否 |
是否危险品 | 是 |
供应商 | Tocris |
生物活性 | Antifungal agent; potent inhibitor of cytochrome P450c17. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 531.44 |
分子式 | C26H28Cl2N4< |
可溶性/溶解性 | Soluble to 50 mM in ethanol and to 75 mM in DMSO |
参考文献 | Dumaineet al (1998) Blockade of HERG and Kv1.5 by ketoconazole. J.Pharmacol.Exp.Ther. 286 727. PMID: 9694927. Kuhn-Veltenet al (1992) Ketoconazole inhibition of the bifunctional cytochrome P450c17 does not affect androgen formation from the endogenous lyase substrate. Biochem.Pharmacol. 44 2371. PMID: 1472102. Ayub and Levell (1989) Inhibition of human adrenal steroidogenic enzymes in vitro by imidazole drugs including ketoconazole. J.Steroid Biochem. 32 515. PMID: 2724954. Merck Index 125313. |