| 货号 | 1708/100 |
| 别名 | 1-(4-Chlorobenzoyl)-5-methoxy-2-met |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Cyclooxgenase (COX) inhibitor; displays selectivity for COX-1 (IC50 values are 230 and 630 nM for human COX-1 and COX-2 respectively). Widely used anti-inflammatory agent. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 357.79 |
| 分子式 | C19H16ClNO4 |
| 可溶性/溶解性 | Soluble to 50 mM in ethanol with gentle warming and to 100 mM in DMSO |
| 参考文献 | Palomeret al (2002) Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models. J.Med.Chem. 45 1402. PMID: 11906281. Shen and Winter (1977) Chemical and biological studies on indomethacin, sulindac and their analogs. Adv.Drug Res. 12 90. PMID: 343530. Walters and Willoughby (1965) Indomethacin, a new anti-inflammatory drug: its potential use as a laboratory tool. J.Pathol.Bacteriol. 90 641. PMID: 5849618. |