| 货号 | 5235/100U |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Potent and selective N-type Ca2+ channel blocker (IC50 ~ 60 nM); selectively and reversibly blocks N-type Ca2+ channels. Does not block T-type Ca2+ channels, K+ channels or Na+ channels. Exhibits analgesic effects in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4437.13 |
| 分子式 | C196H292N50O |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | CIGEGVPCDENDPRCCSGLVCLKPTLHGIW (Modifications: Disulfide bridge: 1-16,8-21,15-36) |
| 参考文献 | Denget al (2014) Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena. Neuropharmacology 79 657. PMID: 24467846. Jianget al (2010) Venomics of the spider Ornithoctonus huwena based on transcriptomic versus proteomic analysis. Comp.Biochem.Physiol.Part D Genomics Proteomics 5 81. PMID: 20403776. |