货号 | 1030/50 |
别名 | [(2,6-Dichlorophenyl)acetyl]guanidi |
是否允许进口 | 否 |
是否危险品 | 是 |
供应商 | Tocris |
生物活性 | Selectiveα2A-adrenoceptor agonist (Kd = 31 nM). Displays 60-fold selectivity over α2B-adrenoceptors. Also available as part of the α2-Adrenoceptor Tocriset™. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 282.56 |
分子式 | C9H9Cl2N3 |
可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
参考文献 | Intengan and Smyth(1997)Alpha-2a/d adrenoceptor subtype stimulation by guanfacine increases osmolar clearance. J.Pharmacol.Exp.Ther. 281 48. PMID: 9103479. Uhlen and Wikberg (1991) Delineation of rat kidney α2A- and α2B-adrenoceptors with [3H]RX821002 radioligand binding: computer modelling reveals that guanfacine is an α2A -selective compound. Eur.J.Pharmacol. 202 235. PMID: 1666366. Merck Index 124590. |