FH 535 (10 MG)
货号:
4344/10 基本售价:
询价 规格:
10 mg
产品信息
概述货号 | 4344/10 |
别名 | 2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide |
是否允许进口 | 否 |
是否危险品 | 是 |
性能供应商 | Tocris |
生物活性 | Inhibitor of Wnt/β-catenin signaling and dual antagonist of PPARγ/δ activity. Suppresses β-catenin/Tcf-mediated transcription; inhibits β-catenin and GRIP1 recruitment to PPARγandδ. Exhibits antiproliferative effects in transformed colon, lung and liver cancer cell lines. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 361.2 |
分子式 | C13H10Cl2N2< |
可溶性/溶解性 | Soluble to 75 mM in DMSO |
参考文献 | Handeli and Simon (2008) A small-molecule inhibitor of Tcf/β-catenin signaling down-regulates PPARγ and PPARδ activities. Mol.Cancer Ther. 7 521. PMID: 18347139. |