| 货号 | 1467/10 |
| 别名 | (8S,10S)-8-Acetyl-10-[(3-amino-2,3, |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Anticancer agent that is clinically used to treat nonlymphocytic leukemia. Inhibits RNA and DNA synthesis and causes DNA fragmentation in vivo. Reduces tau mRNA levels in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 563.99 |
| 分子式 | C27H29NO10.HCl |
| 可溶性/溶解性 | Soluble to 50 mM in water |
| 参考文献 | Dickeyet al (2006) Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression. Mol.Neurodegen. 1 6. PMID: 16930453. Laurent and Jaffrezou (2001) Signaling pathways activated by daunorubicin. Blood 98 913. PMID: 11493433. Gewirtz (1999) A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem.Pharmacol. 57 727. PMID: 10075079. Aubel-Sadron and Londos-Gagliardi (1984) Daunorubicin and doxorubicin, anthracycline antibiotics, a physicochemical and biological review. Biochimie 66 333. PMID: 6380596. |