| 货号 | 0690/100 |
| 别名 | 2-[(2,6-Dichlorophenyl)amino-2-imid |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Prototypical I1 imidazoline receptor ligand. α2-adrenergic receptor agonist. Antihypertensive. Also thought to enhance autophagy; shown to increase LC3-II levels in PC12 cells. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 266.56 |
| 分子式 | C9H9Cl2N3 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 75 mM in DMSO |
| 参考文献 | Williamset al (2008) Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nat.Chem.Biol. 4 295. PMID: 18391949. Armitsuet al (1998) Mechanism of relaxant effect of clonidine in isolated bovine tracheal smooth muscle. J.Pharmacol.Exp.Ther. 286 681. PMID: 9694921. Silvaet al (1996) Dual effect of clonidine on mesenteric artery adrenoreceptors: agonistic (alpha-2) and antagonistic (alpha-1). J.Pharmacol.Exp.ther. 277 872. PMID: 8627569. Greneyet al (1994) Isolation of a human cerebral imidazoline-specific binding protein. Eur.J.Pharmacol. 265 R1. PMID: 7883019. Ernsbergeret al (1987) Clonidine binds to imidazole binding sites as well as α2-adrenoceptors in the ventrolateral medulla. Eur.J.Pharmacol. 134 1. PMID: 3030779. Merck Index 122450. |