| 货号 | 0962/100 |
| 别名 | 8-[4-[4-(2-Pyrimidinyl)-1-pipirazin |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Classic 5-HT1A partial agonist with relatively high affinity (Ki = 9.3 - 29.5 nM). A clinically effective anxiolytic. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 421.97 |
| 分子式 | C21H31N5O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in water |
| 参考文献 | Gobertet al (1999) Buspirone modulates basal and fluoxetine-stimulated dialysate levels of dopamine, noradrenaline and serotonin in the frontal cortex of freely moving rats: activation of serotonin1A receptors and blockade of α2-adrenoceptors underlie its action. Neuroscience 93 1251. PMID: 10501449. Cao and Rodgers (1997) Comparative behavioural profiles of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine (1-PP) in the murine elevated plus-maze. Neuropharmacology 36 1089. PMID: 9294974. Goa and Ward (1986) Buspirone - a preliminary review on its pharmacological properties and therapeutic efficacy as an anxiolytic. Drugs 32 114. PMID: 2874976. Merck Index 121528. |