| 货号 | 1290/10 |
| 别名 | (2R,3S,4S)-2-[(4-Methoxyphenyl)meth |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Protein synthesis inhibitor (blocks translation). Potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase. Acts as a potent signaling agonist to selectively elicit homologous desensitization of immediate early gene induction (c-fos, fosB, c-jun, junB and junD). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 265.31 |
| 分子式 | C14H19NO4 |
| 可溶性/溶解性 | Soluble to 50 mM in ethanol and to 100 mM in DMSO |
| 参考文献 | Croonset al (2009) The protein synthesis inhibitor anisomycin induces macrophage apoptosis in rabbit atherosclerotic plaques through p38 mitogen-activated protein kinase. J.Pharmacol.Exp.Ther. 329 856. PMID: 19286921. Hazzalinet al (1998) Anisomycin selectively desensitizes signalling components involved in stress kinase activation and fosandjun induction. Mol.Cell.Biol. 18 1844. PMID: 9528756. Canoet al (1994) Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun. Mol.Cell.Biol. 14 7352. PMID: 7935449. Kyriakiset al (1994) The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369 156. PMID: 8177321. Sanchezet al (1994) Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372 794. PMID: 7997269. |