| 货号 | 5195/10U |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | PotentShakerK+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4090.87 |
| 分子式 | C169H278N54O |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | GVPINVSCTGSPQCIKPCKDAGMRFGKCMN (Modifications: Disulfide bridge: 8-28,14-33,18-35) |
| 参考文献 | Anangiet al (2012) Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockers. PLoS ONE 7 e52965. PMID: 23300835. Grosset al (1996) Agitoxin footprinting the shaker potassium channel pore. Neuron 16 399. PMID: 8789954. Garciaet al (1994) Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry 33 6834. PMID: 8204618. |