| 货号 | 1297/10 |
| 别名 | 4-[(1R,6R)-3-Methyl-6-(1-methylethe |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Neurobehaviorally inactive cannabinoid that acts as a selective agonist for GPR55 (EC50 values are 2.5, >30 and >30 μM at GPR55, CB1 and CB2 receptors respectively). Increases phosphorylation of protein kinases in, and migration of, human umbilical vein endothelial cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 314.47 |
| 分子式 | C21H30O2 |
| 可溶性/溶解性 | Soluble in methyl acetate (supplied pre-dissolved - 5mg/ml) |
| 参考文献 | Ryberget al (2007) The orphan receptor GPR55 is a novel cannabinoid receptor. Br.J.Pharmacol. 152 1092. PMID: 17876302. Moet al (2004) Atypical cannabinoid stimulates endothelial cell migration via a Gi/Go-coupled receptor distinct from CB1, CB2 or EDG-1. Eur.J.Pharmacol. 489 21. PMID: 15063151. Ho and Hiley (2003) Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery. Br.J.Pharmacol. 138 1320. PMID: 12711633. Jaraiet al (1999) Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc.Natl.Acad.Sci.U.S.A. 96 14136. PMID: 10570211. |