| 货号 | 4539/10 |
| 别名 | (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of carnitine palmitoyltransferase I (CPT1); inhibits β-oxidation in mitochondria. Shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 320.74 |
| 分子式 | C15H18ClNaO4 |
| 可溶性/溶解性 | Soluble to 20 mM in water and to 20 mM in DMSO with gentle warming |
| 参考文献 | Xuet al (2003) Etomoxir mediates differential metabolic channeling of fatty acid and glycerol precursors into cardiolipin in H9c2 cells. J.Lipid Res. 44 415. PMID: 12576524. Ruppet al (1992) Modification of subcellular organelles in pressure-overloaded heart by etomoxir, a carnitine palmitoyltransferase I inhibitor. FASEB J. 6 2349. PMID: 1531968. Agiuset al (1991) Stereospecificity of the inhibition of etomoxir of fatty acid and cholesterol synthesis in isolated rat hepatocytes. Biochem.Pharmacol. 42 1717. PMID: 1930298. |