| 货号 | 0684/10 |
| 别名 | (±)-exo-2-(6-Chloro-3-pyridinyl)-7-a |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | High affinity nicotinic agonist (Ki values are 0.02 and 233 nM for α4β2 and α7 nicotinic receptors respectively). Analgesic. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 计算分子量 | 208.69 |
| 分子式 | C11H13ClN2 |
| 可溶性/溶解性 | Soluble to 5 mM in water and to 100 mM in ethanol |
| 参考文献 | Sharpleset al (2000) UB-165 implicates α4β2 nAChR in striatal dopamine release. J.Neurosci. 20 2783. PMID: 10751429. Markset al (1998) Differential agonist inhibition identifies multiple epibatidine binidng sites in mouse brain. J.Pharmacol.Exp.Ther. 285 377. PMID: 9536034. Gerzarichet al (1995) Comparative pharmacology of epibatidine; a potent agonist for neuronal nicotinic acetylcholine receptors. Mol.Pharmacol. 48 774. PMID: 7476906. Badio and Daly (1994) Epibatidine, a potent analgesic and nicotinic agonist. Mol.Pharmacol. 45 563. PMID: 8183234. Spandeet al (1992) Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity. J.Am.Chem.Soc. 1143475. |