| 货号 | 1971/50 |
| 别名 | (S)-(+)-3-(2-Piperidinyl)pyridine hydrochloride |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | High affinity neuronal nicotinic ACh receptor partial agonist (Ki values are 0.058, 0.26 and 7.2 μM for rat α7, rat α4β2 and fish skeletal muscle nAChRs respectively). Also stimulates Ca2+-dependent catecholamine release from rat adrenomedullary cells in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 198.69 |
| 分子式 | C10H14N2.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| 参考文献 | Honget al (2007) Effect of anabasine on catecholamine secreation from the perfused rat adrenal medulla. J.Cardiol. 50 351. PMID: 18186309. Luet al (1999) Desensitization of nicotinic agonist-induced [3H]γ-aminobutyric acid release from mouse brain synaptosomes is produced by subactivating concentrations of agonists. J.Pharmacol.Exp.Ther. 291 1127. PMID: 10565833. Parkeret al (1998) Neuronal nicotinic receptor β2 and β4 subunits confer large differences in agonist binding affinity. Mol.Pharmacol. 54 1132. PMID: 9855644. Kemet al (1997) Anabaseine is a potent agonist on muscle and neuronal alpha-bungarotoxin-sensitive nicotinic receptors. J.Pharmacol.Exp.Ther. 283 979. PMID: 9399967. |