L3MBTL1 MBT Domains TR-FRET Assay Kit
货号:
601030-9600Well 基本售价:
116382.0 元 规格:
9600 wells
产品信息
概述货号 | 601030-9600Well |
描述 | The post-translational modification (PTM) of chromatin plays a crucial role in the regulation of gene transcription, DNA repair and many other cellular processes. Collectively, the combinatorial array of chromatin PTMs forms the foundation of the “Histone Code”. This code is interpreted by a large family of protein motifs that selectively recognize and bind to a particular chromatin PTM. Commonly found in transcription factors and other regulatory proteins, these reader domains localize their proteins to chromatin bearing the appropriate PTM(s). Additionally, a given protein will often have multiple reader domains located adjacent to each other, potentially providing additional levels of specificity to the system. Cayman’s L3MBTL1 MBT Domains TR-FRET Assay Kit is a homogeneous, TR-FRET assay method amenable to rapid characterization of Tudor domain inhibitors in a high-throughput format. This screening assay is robust, displaying a Zʹ >0.6, and is designed to assist in the early-stage discovery and development of chromatin reader domain inhibitors. |
别名 | H-l(3)MBT;Lethal(3)Malignant Brain Tumor-like Protein 1;L(3)MBT-like; |
性能供应商 | Cayman |
运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
稳定性 | ≥ 6 months |
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