Butenoyl PAF
货号：
60929-50mg 基本售价：
31360.0 元 规格：
50 mg
产品信息
概述| 货号 | 60929-50mg |
| 描述 | Butenoyl and butanoyl PAF are both products of the oxidative decomposition of 2-arachidonoyl phospholipids.1 Oxygenation of C-5 of the 5,6 double bond followed by cleavage of the hydroperoxide results in a PAF-like compound with a 4-carbon residue esterified in the sn-2 position; similar oxidized lipid products also act as ligands for oxidized lipid receptors and peroxisome proliferator-activated receptor.2 Although butenoyl PAF is 10-fold less potent than PAF as a PAF receptor agonist, it is present in amounts 100-fold greater than enzymatically generated PAF. Therefore, oxidation of LDL phospholipids generates physiologically relevant bioactive PAF-like molecules. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Marathe, G.K.,Davies, S.S.,Harrison, K.A., et al. Inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines. The Journal of Biological Chemisty 274, 28395-28404 (1999).
2.Davies, S.S.,Pontsler, A.V.,Marathe, G.K., et al. Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor γ ligands and agonists. The Journal of Biological Chemisty 276, 16015-16023 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 549.7 |
| 分子式 | C28H56NO7P |
| CAS号 | 474944-25-7 |
| 稳定性 | ≥ 1 year |
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