| 货号 | 0975/50 |
| 别名 | (2S,2'R,3'R)-2-(2',3'-Dicarboxycyclopro |
| 供应商 | Tocris |
| 生物活性 | Presynaptic depressant; highly potent agonist for group II mGlu receptors. Also available as part of the Group II mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 203.15 |
| 分子式 | C7H9NO6 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 147782-19-2 |
| 参考文献 | Brabetet al (1998) Comparative effect of L-CCG-I, DCG-IV and γ-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes. Neuropharmacology 37 1043. PMID: 9833633. Cartmellet al (1998) Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxycyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes. Br.J.Pharmacol. 123 497. PMID: 9504391. Ishidaet al (1993) A novel metabotropic receptor agonist: marked depression of monosynaptic excitation in the isolated rat spinal cord. Br.J.Pharmacol. 109 1169. PMID: 8401927. Ohfuneet al (1993) Synthesis of L-2-(2,3-dicarboxycyclopropyl)-glycines. Novel conformationally restricted glutamate analogues. Bioorg.Med.Chem.Lett. 315. |