17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
货号：
10010061-50mg 基本售价：
28910.0 元 规格：
50 mg
产品信息
概述| 货号 | 10010061-50mg |
| 描述 | Prostaglandin F2α(PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.1,2,3 17-trifluoromethylphenyl trinor Prostaglandin F2α (17-trifluoromethylphenyl trinor PGF2α) is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α ethyl amide is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Ethyl amides of PGs can serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid. |
| 别名 | 17-trifluoromethylphenyl trinor PGF2α ethyl amide; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Samuelsson, B.,Goldyne, M.,Granström, E., et al. Prostaglandins and thromboxanes. Annual Reviews of Biochemistry 47, 997-1029 (1978).
2.Speroff, L., and Ramwell, P.W. Prostaglandins in reproductive physiology. American Journal of Obstetics and Gynecology 107, 1111-1130 (1970).
3.Crankshaw, D.J., and Gaspar, V. Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes. Journal of Reproduction and Fertility 103, 55-61 (1995).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | >98% |
| 计算分子量 | 483.6 |
| 分子式 | C26H36F3NO4 |
| CAS号 | 1621369-73-0 |
| 稳定性 | ≥ 1 year |
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