15(S)-Latanoprost
货号：
16818-50mg 基本售价：
27930.0 元 规格：
50 mg
产品信息
概述| 货号 | 16818-50mg |
| 描述 | 15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 µg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.1 15(S)-Latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product. |
| 别名 | 15-epiLatanoprost; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Resul, B.,Stjernschantz, J.,No, K., et al. Phenyl-substituted prostaglandins: Potent and selective antiglaucoma agents. Journal of Medicinal Chemistry 36, 243-248 (1993).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 432.6 |
| 分子式 | C26H40O5 |
| CAS号 | 145773-22-4 |
| 稳定性 | ≥ 2 years |
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