Orexin A (bovine, human, mouse, rat)
货号：
15073-5mg 基本售价：
26320.0 元 规格：
5 mg
产品信息
概述| 货号 | 15073-5mg |
| 描述 | Orexin A is a 33 amino acid hypothalamic neuropeptide with a role in appetite regulation, wakefulness, locomotor activity, hypothalamic-pituitary-adrenal activity, and pain thresholds.1 Orexin signaling is activated by nutrient depletion, causing an increase in food intake by delaying the signals of satiety.2 It activates the orexin-1 and -2 receptors with equal affinity (EC50s = 0.09 and 0.06 μM, respectively).3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Rodgers, R.J.,Ishii, Y.,Halford, J.C.G., et al. Orexins and appetite regulation. Neuropeptides 36(5), 303-325 (2002).
2.Schwartz, M.W. Orexins and appetite: The big picture of energy homeostasis gets a little bigger. Nature Medicine 4, 385-386 (1998).
3.Lang, M.,Söll, R.M.,Dürrenberger, F., et al. Structure-activity studies of orexin A and orexin B at the human orexin 1 and orexin 2 receptors led to orexin 2 receptor selective and orexin 1 receptor preferring ligands. Journal of Medicinal Chemistry 47(5), 1153-1160 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 3561.1 |
| CAS号 | 205640-90-0 |
| 稳定性 | ≥ 2 years |
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