| 货号 | 10541-5mg |
| 描述 | Linoleic acid alkyne is an ω-alkyne derivative of linoleic acid (Item No. 90150). The ω-alkyne moiety allows Cu(I)-catalyzed cycloaddition chemistry with other molecules containing an azide group.1,2 Linoleic acid alkyne has been used in experiments focusing on the biological roles of linoleic acid.3,4 Alternatively, this modified lipid can be used to synthesize other alkyne-containing products, such as glycerophospholipids, for click chemistry.5 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Gaebler, A.,Penno, A.,Kuerschner, L., et al. A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins. J. Lipid. Res. 57(10), 1934-1947 (2016). 2.Grammel, M. and Hang, H.C. Chemical reporters for biological discovery. Nat. Chem. Biol. 9(8), 475-484 (2013). 3.Beavers, W.N.,Serwa, R.,Shimozu, Y., et al. ω-Alkynyl lipid surrogates for polyunsaturated fatty acids: Free radical and enzymatic oxidations. Journal of the American Chemical Society 136(32), 11529-11539 (2014). 4.Windsor, K.,Genaro-Mattos, T.C.,Kim, H.-Y.H., et al. Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome. J. Lipid. Res. 54(10), 2842-2850 (2013). 5.Milne, S.B.,Tallman, K.A.,Serwa, R., et al. Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry. Nat. Chem. Biol. 6(3), 205-207 (2010). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 276.4 |
| 分子式 | C18H28O2 |
| CAS号 | 1219038-31-9 |
| 稳定性 | ≥ 1 year |
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