| 货号 | 20110-500ug |
| 描述 | Leukotriene B4(LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway.1,2,3 It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. In subnanomolar ranges (3.9 x 10−10 M), LTB4 causes chemotaxis and chemokinesis in human polymorphonuclear leukocytes.4 At higher concentrations, (1.0 x 10−7 M), LTB4 leads to neutrophil aggregation and degranulation as well as superoxide anion production.4,5 |
| 别名 | LTB4; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Rådmark, O.,Malmsten, C.,Samuelsson, B., et al. Leukotriene A: Stereochemistry and enzymatic conversion to leukotriene B. Biochemical and Biophysical Research Communications 92, 954-961 (1980). 2.Ford-Hutchinson, A.W.,Bray, M.A.,Doig, M.V., et al. Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature 286, 264-265 (1980). 3.McGee, J. and Fitzpatrick, F. Enzymatic hydration of leukotriene A4. The Journal of Biological Chemisty 260, 12832-12837 (1985). 4.Ford-Hutchinson, A.W. Leukotriene B4 in inflammation. Critical Reviews in Immunology 10, 1-12 (1990). 5.McMillan, R.M. and Foster, S.J. Leukotriene B4 and inflammatory disease. Agents and Actions 24, 114-119 (1988). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 336.5 |
| 分子式 | C20H32O4 |
| CAS号 | 71160-24-2 |
| 稳定性 | ≥ 1 year |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |