| 货号 | 5064/50 |
| 别名 | (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[ |
| 供应商 | Tocris |
| 生物活性 | Sodium salt of LY 379268 (Cat. No. 2453), a highly selective group II mGlu receptor agonist. |
| 运输条件 | Ambient |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 231.11 |
| 分子式 | C7H7NNa2O5 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| 参考文献 | Colladoet al (2002) (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-methylcyclopropyl) glycine is a potent and selective metabotropic group 2 agonist with anxiolytic properties. J.Med.Chem. 45 3619. PMID: 12166935. Bondet al (2000) Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: investigations into possible mechanisms of action in vivo. J.Pharmacol.Exp.Ther. 294 800. PMID: 10945827. Bondet al (1999) LY379268, a potent and selective group II metabotropic glutamate receptor agonist, is neuroprotective in gerbil global, but not focal cerebral ischaemia. Neurosci.Lett. 273. PMID: 10515191. |