| 货号 | 0320/50 |
| 别名 | (S)-4C3HPG |
| 供应商 | Tocris |
| 生物活性 | Competitive antagonist at group I mGlu1a/1a receptors, mixed effect at mGlu5a/5b receptors; agonist at group II metabotropic glutamate receptors. (RS)-4-Carboxy-3-hydroxyphenylglycine (Cat. No. 0310) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 211.17 |
| 分子式 | C9H9NO5 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH and to 5 mM in water |
| CAS号 | 85148-82-9 |
| 参考文献 | Sekiyamaet al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493. PMID: 8730745. Kingstonet al (1995) Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects mGluR1α and mGluR5a subtypes. Neuropharmacology 34 887. PMID: 8532170. Hayashiet al (1994) Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor sub-types. J.Neurosci. 14 3370. PMID: 8182479. Birseet al (1993) Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system Neuroscience 52 481. PMID: 7680790. |