Fumonisin B2
货号：
13227-10mg 基本售价：
19404.0 元 规格：
10 mg
产品信息
概述| 货号 | 13227-10mg |
| 描述 | Fumonisin B2 is a mycotoxin originally isolated from F. moniliforme, a prevalent fungus of corn and other grains.1 Fumonisins cause food poisoning in livestock and humans following the consumption of Fusarium-infested corn.1 Fumonisin B2, like fumonisin B1 (Item No. 62580), structurally resembles sphingosine and, at 1 μM, inhibits sphingosine N-acyltransferase (>90%) in hepatocytes.2 Fumonisins induce apoptosis via altered sphingolipid metabolism, resulting in hepatotoxicity and nephrotoxicity. It is now known that fumonisins are produced by fungi other than F. moniliforme and occur as contaminants in a wide variety of foods. |
| 别名 | FB2; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gelderblom, W.C.A.,Jaskiewicz, K.,Marasas, W.F.O., et al. Fumonisins - novel mycotoxins with cancer-promoting activity produced by Fusarium moniliforme. Applied and Environmental Microbiology 54, 1806-1811 (1988).
2.Wang, E.,Norred, W.P.,Bacon, C.W., et al. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. The Journal of Biological Chemisty 266, 14486-14490 (1991).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 705.8 |
| 分子式 | C34H59NO14 |
| CAS号 | 116355-84-1 |
| 稳定性 | ≥ 2 years |
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