| 货号 | 10009029-10mg |
| 描述 | 6-hydroxy Chlorzoxazone is a CYP2E1 metabolite of chlorzoxazone.1,2,3,4 |
| 别名 | NSC 24955; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Scott, R.J.,Palmer, J.,Lewis, I.A.S., et al. Determination of a «GW cocktail» of cytochrome P450 probe substrate and their metabolites in plasma and urine using automated solid phase extraction and fast gradient liquid chromatography tandem mass spectrometry. Rapid Communications in Mass Spectrometry 13, 2305-2319 (1999). 2.Frye, R.F.,Adedoyin, A.,Mauro, K., et al. Use of chlorzoxazone as an in vivo probe of cytochrome P450 2E1: Choice of dose and phenotypic trait measure. Journal of Clinical Pharmacology 38, 82-89 (1998). 3.Court, M.H.,Von Moltke, L.L.,Shader, R.I., et al. Biotransformation of chlorzoxazone by heptic microsomes from humans and ten other mammalian species. Biopharmaceutics & Drug Disposition 18, 213-226 (1997). 4.Peter, R.,Bocker, R.,Beaune, P.H., et al. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P450 2E1. Chemical Research in Toxicology 3, 566-573 (1990). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 4 |
| 纯度 | ≥97% |
| 计算分子量 | 185.6 |
| 分子式 | C7H4ClNO3 |
| CAS号 | 1750-45-4 |
| 稳定性 | ≥ 1 year |
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