CAY10406
货号：
72510-100mg 基本售价：
18480.0 元 规格：
100 mg
产品信息
概述| 货号 | 72510-100mg |
| 描述 | CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7.1 The non-trifluoromethyl compound exhibits Ki values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are effector caspases that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently available for caspase inhibition by CAY10406. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Lee, D.,Long, S.A.,Murray, J.H., et al. Potent and selective nonpeptide inhibitors of caspases 3 and 7. Journal of Medicinal Chemistry 44, 2015-2026 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 512.5 |
| 分子式 | C27H23F3N2O5S |
| 稳定性 | ≥ 1 year |
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