货号 | 10011300-10mg |
描述 | 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) that contains stearic acid in the sn-1 site and arachidonic acid at the sn-2 position of the glycerol backbone, as is commonly found in DAG from biological phospholipids. NBD-Stearoyl-2-arachidonoyl-sn-glycerol has the fluorophore nitrobenzoxadiazole (NBD) attached to the ω-end of the stearoyl chain of 1-stearoyl-2-arachidonoyl-sn-glycerol. Fluorescently tagged lipids have been used to study their interactions with proteins, their utilization by cells and liposomes, and for the development of assays for lipid metabolism.1,2,3,4,5 |
别名 | NBD-SAG; |
供应商 | Cayman |
应用文献 | |
1.Kumagai, K.,Yasuda, S.,Okemoto, K., et al. CERT mediates intermembrane transfer of various molecular species of ceramides. The Journal of Biological Chemisty 280(8), 6488-6495 (2005). 2.Luo, M.,Jones, S.M.,Peters-Golden, M., et al. Nuclear localization of 5-lipoxygenase as a determinant of leukotriene B4 synthetic capacity. Proceedings of the National Academy of Sciences of the United States of America 100(21), 12165-12170 (2003). 3.Moreno, M.J.,Estronca, L.M.B.B., and Vaz, W.L.C. Translocation of phospholipids and dithionite permeability in liquid-ordered and liquid-disordered membranes. Biophysical Journal 91, 873-881 (2006). 4.Loidl, A.,Claus, R.,Deigner, H.P., et al. High-precision fluorescence assay for sphingomyelinase activity of isolated enzymes and cell lysates. Journal of Lipid Research 43, 815-823 (2002). 5.Tani, M.,Okino, N.,Mitsutake, S., et al. Specific and sensitive assay for alkaline and neutral ceramidases involving C12-NBD-ceramide. Journal of Biochemistry 125, 746-749 (1999). | |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 823.1 |
分子式 | C47H74N4O8 |
稳定性 | ≥ 1 year |
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