Butanoyl PAF
货号：
60928-50mg 基本售价：
17150.0 元 规格：
50 mg
产品信息
概述| 货号 | 60928-50mg |
| 描述 | Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate polymorphonuclear leukocytes.1 One of these substances was recently isolated and purified from oxLDL, and identified as azelaoyl PC.2 Butanoyl PAF is a closely related compound which retains at least 10% of the agonist potency of platelet-activating factor (PAF) itself.3 Further, butanoyl PAF is present in oxLDL in amounts more than 100 times greater than enzymatically generated PAF. Butanoyl PAF is therefore one of the important signalling molecules present in oxLDL. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Tontonoz, P.,Nagy, L.,Alvarez, J.G.A., et al. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93, 241-252 (1998).
2.Davies, S.S.,Pontsler, A.V.,Marathe, G.K., et al. Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor γ ligands and agonists. The Journal of Biological Chemisty 276, 16015-16023 (2001).
3.Marathe, G.K.,Davies, S.S.,Harrison, K.A., et al. Inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines. The Journal of Biological Chemisty 274, 28395-28404 (1999).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 551.7 |
| 分子式 | C28H58NO7P |
| CAS号 | 85405-03-4 |
| 稳定性 | ≥ 1 year |
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