| 货号 | 1524/50 |
| 别名 | (4S,5R)-N-(4-Bromophenyl)-3-oxo-4,5 |
| 供应商 | Tocris |
| 生物活性 | Selective CCK2 receptor antagonist (IC50 values are 16 and > 30,000 nM for CCK2 and CCK1 respectively). Displays anxiolytic and antipsychotic properties in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 436.3 |
| 分子式 | C22H18BrN3O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 147523-65-7 |
| 参考文献 | Heltonet al (1996) Central nervous system characterization of the new cholecystokininB antagonist LY288513. Pharmacol.Biochem.Behav. 53 493. PMID: 8866946. Rasmussen (1994) CCK, schizophrenia, and anxiety. CCK-B antagonists inhibit the activity of brain dopamine neurons. Ann.N.Y.Acad.Sci. 713 300. PMID: 8185172. Rasmussenet al (1992) Electrophysiological effects of diphenylpyrazolidinone cholecystokinin-B and cholecystokinin-A antagonists on midbrain dopamine neurons. J.Pharmacol.Exp.Ther. 264480. |