Arachidonoyl Ethanolamide-d4
货号：
10011178-10mg 基本售价：
16856.0 元 规格：
10 mg
产品信息
概述| 货号 | 10011178-10mg |
| 描述 | Arachidonoyl ethanolamide-d4(AEA-d4) contains four deuterium atoms at the hydroxyethyl 1,1,2, and 2 positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain.1 It is an endogenous cannabinoid neurotransmitter that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors and mimics the pharmacologic effects of Δ9-THC.2 AEA inhibits the specific binding of [3H]-HU-243 to synaptosomal membranes with a Ki value of 52 nM, compared to 46 nM for Δ9-THC.1 |
| 别名 | AEA-d4;Anandamide-d4; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Devane, W.A.,Hanus, L.,Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258, 1946-1949 (1992).
2.Felder, C.C.,Briley, E.M.,Axelrod, J., et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America 90, 7656-7660 (1993).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d4) |
| 计算分子量 | 351.6 |
| 分子式 | C22H33D4NO2 |
| CAS号 | 946524-40-9 |
| 稳定性 | ≥ 1 year |
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