Indolmycin
货号：
15385-5mg 基本售价：
16758.0 元 规格：
5 mg
产品信息
概述| 货号 | 15385-5mg |
| 描述 | Indolmycin is an antibiotic isolated from various Streptomyces strains that functions by competitively inhibiting the prokaryotic tryptophanyl-tRNA synthetase (IC50 = 30 μM) without significantly affecting the corresponding eukaryotic synthetase.1,2 It exhibits antibacterial activity against mupirocin- and fusidic acid-resistant strains of Staphylococci.3 |
| 别名 | PA 155A;TAK-083; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Werner, R.G.,Thorpe, L.F.,Reuter, W., et al. Indolmycin inhibits prokaryotic tryptophanyl-tRNA ligase. European Journal of Biochemistry 68(1), 1-3 (1976).
2.Bogosian, G.,Haydock, P.V. and Somerville, R.L. Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coli. Journal of Bacteriology 153(2), 1120-1123 (1983).
3.Hurdle, J.G.,ONeill, A.J. and Chopra, I. Anti-staphylococcal activity of indolmycin, a potential topical agent for control of staphylococcal infections. Journal of Antimicrobial Chemotherapy 52(4), 549-552 (2004).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% |
| 计算分子量 | 257.3 |
| 分子式 | C14H15N3O2 |
| CAS号 | 21200-24-8 |
| 稳定性 | ≥ 2 years |
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