(E)-2-Hexadecenal Alkyne
货号：
20714-5mg 基本售价：
16688.0 元 规格：
5 mg
产品信息
概述| 货号 | 20714-5mg |
| 描述 | (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal (Item No. 17566) that can be used as a click chemistry probe.1 (E)-2-Hexadecenal has been shown to induce cytoskeletal reorganization that results in cell rounding, detachment, activation of downstream JNK targets, and eventual apoptosis in various cell types.2 It reacts readily with deoxyguanosine and DNA to form aldehyde-derived DNA adducts.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Lin, H.-Y.,Haegele, J.A.,Disare, M.T., et al. A generalizable platform for interrogating target- and signal-specific consequences of electrophilic modifications in redox-dependent cell signaling. J. Am. Chem. Soc. 137(19), 6232-6244 (2015).
2.Kumar, A.,Byun, H.S.,Bittman, R., et al. The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner. Cellular Signalling 23(7), 1144-1152 (2011).
3.Upadhyaya, P.,Kumar, A.,Byun, H.S., et al. The sphingolipid degradation product trans-2-hexadecenal forms adducts with DNA. Biochemical and Biophysical Research Communications 424(1), 18-21 (2012).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 234.4 |
| 分子式 | C16H26O |
| CAS号 | 1778692-99-1 |
| 稳定性 | ≥ 2 years |
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