| 货号 | 0323/50 |
| 别名 | (S)-4CPG |
| 供应商 | Tocris |
| 生物活性 | Competitive group I metabotropic glutamate receptor antagonist, with selectivity for mGlu1a/1a over mGlu5a/5b. (RS)-4-Carboxyphenylglycine (Cat. No. 0321) and (R)-4-Carboxyphenylglycine (Cat. No. 0322) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 195.17 |
| 分子式 | C9H9NO4 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH with gentle warming |
| CAS号 | 134052-73-6 |
| 参考文献 | Dohertyet al (1999) Antagonist activity of α-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells. Br.J.Pharmacol. 126 205. PMID: 10051137. Brabetet al (1995) Phenylglycine derivatives discriminate between mGluR1-and mGluR5-mediated responses. Neuropharmacology 34 895. PMID: 8532171. Birseet al (1993) Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience 52 481. PMID: 7680790. Eatonet al (1993) Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine (CPG) and (RS)-α-methyl-4-carboxyphenylglycine (MCPG). Eur.J.Pharmacol. 244 195. PMID: 8381746. |