货号 | 16704-1mg |
描述 | Eicosapentaenoic acid (EPA; Item No. 90110) is an ω-3 fatty acid abundantly available in marine organisms that has been shown to offer anti-inflammatory and cardiovascular benefits.1,2 EPA alkyne is a form of EPA with an ω-terminal alkyne. The terminal alkyne group can be used in click chemistry linking reactions to tag EPA with fluorescent or biotinylated labels for analysis of its metabolism and biological activity.3,4 Because the alkyne group is at the ω-terminus, this compound can be used to easily tag metabolites and derivatives. |
别名 | EPA Alkyne;Click Tag™ EPA Alkyne; |
供应商 | Cayman |
应用文献 | |
1.Yerram, N.R.,Moore, S.A. and Spector, A.A. Eicosapentaenoic acid metabolism in brain microvessel endothelium: Effect on prostaglandin formation. Journal of Lipid Research 30, 1747-1757 (1989). 2.Takeuchi, H.,Inoue, J.,Yoshida, M., et al. Dietary effects of n-3 eicosapentaenoic acid on essential fatty acid-deficiency symptoms of rats. Agricultural and Biological Chemistry 53, 3225-3232 (1989). 3.Kolb, H.C. and Sharpless, K.B. The growing impact of click chemistry on drug discovery. Drug Discovery Today 8(24), 1128-1137 (2003). 4.Lutz, J.F. and Zarafshani, Z. Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide-alkyne "click" chemistry. Advanced Drug Delivery Reviews 60, 958-970 (2008). | |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 298.4 |
分子式 | C20H26O2 |
稳定性 | ≥ 1 year |
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