C-6 NBD-dihydro-Ceramide
货号：
10007957-10mg 基本售价：
16240.0 元 规格：
10 mg
产品信息
概述| 货号 | 10007957-10mg |
| 描述 | C-6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C-6 ceramide in the inhibition of viral glycoprotein transport through the Golgi.1 C-6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase2 and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane.3 C-6 NBD-dihydro-Ceramide is structurally identical to C-6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone. |
| 别名 | C-6 NBD-dihydro-Ceramide (d18:0/6:0);N-C6-NBD-D-erythro-dihydro-Sphingosine; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Rosenwald, A.G., and Pagano, R.E. Inhibition of glycoprotein traffic through the secretory pathway by ceramide. The Journal of Biological Chemisty 268, 4577-4579 (1993).
2.Paul, P.,Kamisaka, Y.,Marks, D.L., et al. Purification and characterization of UDP-glucose: Ceramide glucosyltransferase from rat liver Golgi membranes. The Journal of Biological Chemisty 271, 2287-2293 (1996).
3.Lipsky, N.G., and Pagano, R.E. Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: Endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the golgi apparatus en route to the plasma membrane. Journal of Cell Biology 100, 27-34 (1985).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 577.8 |
| 分子式 | C30H51N5O6 |
| CAS号 | 114301-97-2 |
| 稳定性 | ≥ 2 years |
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