CAY10512
货号：
10009536-500mg 基本售价：
16170.0 元 规格：
500 mg
产品信息
概述| 货号 | 10009536-500mg |
| 描述 | The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 µM compared to 20 µM by resveratrol.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Heynekamp, J.J.,Weber, W.M.,Hunsaker, L.A., et al. Subsitituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor α-induced activation of transcription factor nuclear factor κB. Journal of Medicinal Chemistry 49, 7182-7189 (2006).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 228.3 |
| 分子式 | C15H13FO |
| CAS号 | 139141-12-1 |
| 稳定性 | ≥ 2 years |
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