MLi-2 ( )
货号：
5756/50 基本售价：
15605.4 元 规格：
50 mg
产品信息
概述| 货号 | 5756/50 |
| 别名 | rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective LRRK2 inhibitor (IC50 = 0.76-3.4 nM depending on assay). Exhibits >295-fold selectivity for over 300 kinases and a diverse panel of receptors and ion channels. Centrally bioavailable and active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 379.46 |
| 分子式 | C21H25N5O2 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Fellet al (2015) MLi-2, a potent, selective, and centrally active compound for exploring the therapeutic potential and safety of LRRK2 kinase inhibition. J.Pharmacol.Exp.Ther. 355 397. PMID: 26407721. |
