| 货号 | 4824/50 |
| 别名 | N-[5-[3,4-Difluoro-2-[(2-fluoro-4-i |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of MEK1. Analog of PD 184352 (Cat. No. 4237). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 545.3 |
| 分子式 | C20H19F3IN5< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| 参考文献 | Zhanget al (2009) Targeting cancer with small molecule kinase inhibitors. Nat.Rev.Cancer 9 28. PMID: 19104514. Ohrenet al (2004) Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel competitive kinase inhibition. Nat.Struct.Mol.Biol. 11 1192. PMID: 15543157. |