KB SRC 4 (50 MG)
货号：
4660/50 基本售价：
15545.9 元 规格：
50 mg
产品信息
概述| 货号 | 4660/50 |
| 别名 | 1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective c-Src inhibitor (Ki = 44 nM); does not inhibit c-Abl at concentrations up to 125 μM. Selective between Src family members (Kd values are 86, 160, 240, 720, 3200, 4400, and >40,000 nM for c-Src, Lck, Fgr, Yes, Lyn, Hck and Fyn respectively). Significantly inhibits cell growth in 4T1 mammary carcinoma tumor cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 555.03 |
| 分子式 | C32H23ClN8 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Brandvoldet al (2012) Development of a highly selective c-Src kinase inhibitor. ACS Chem.Biol. 7 1393. PMID: 22594480. |
